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J Med Genet. 1987 Nov;24(11):649-58.

The molecular genetics of human chromosome 6.

Author information

1
Human Immunogenetics Laboratory, Imperial Cancer Research Fund, Lincoln's Inn Fields, London.

Abstract

Chromosome 6 contains several clinically important markers as well as classical enzyme loci, proto-oncogenes, and a growing number of anonymous DNA restriction fragment length polymorphisms (RFLPs). It is also of unique interest because of the location of the major histocompatibility complex (MHC) on the short arm, at 6p21.3. The MHC is one of the most detailed areas of the human genetic map to date and many important diseases, some of a suspected autoimmune aetiology, are associated with it.

PMID:
3323517
PMCID:
PMC1050341
[Indexed for MEDLINE]
Free PMC Article

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