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Drugs. 1987;34 Suppl 2:15-22.

Classification of cephalosporins.

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1
Department of Medical Microbiology, London Hospital Medical College, University of London.

Abstract

Many cephalosporins are now in clinical use. They have a wide range of activity against different species of bacteria and also differ in their pharmacokinetic and metabolic characteristics. This article outlines a basis for comparison and classification of cephalosporins into 4 groups active mainly against: (1) Gram-positive bacteria; (2) Gram-negative rods; (3) Gram-negative rods including Pseudomonas spp.; and (4) Gram-negative rods including Bacteroides spp. Further subdivisions highlight the pharmacological differences.

PMID:
3319498
[Indexed for MEDLINE]
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