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Bull Eur Physiopathol Respir. 1987 Jul-Aug;23(4):397-400.

The relevance of hyperresponsiveness but not of atopy to FEV1 decline. Preliminary results in a working population.

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1
INSERM U 169, Villejuif, France.

Abstract

Five-year FEV1 decline in 329 working men was shown to be significantly related only among eversmokers to methacholine bronchial hyperresponsiveness (assessed at the end of follow-up), allergic rhinitis and rhinitis induced by cold air, independent of asthma and FEV1 level. Positive skin prick test was not associated with FEV1 decline.

PMID:
3318969
[Indexed for MEDLINE]

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