Format

Send to

Choose Destination
See comment in PubMed Commons below
Am J Med. 1987 Nov 20;83(5A):81-3.

Double-blind clinical trial of S-adenosylmethionine versus ibuprofen in the treatment of osteoarthritis.

Author information

1
Rheumazentrum Bad Abbach, II Medizinische Klinik, Bad Abbach, Federal Republic of Germany.

Abstract

Thirty-six subjects with osteoarthritis of the knee, the hip, and/or the spine were enrolled in a randomized double-blind study. Patients received a daily oral dose of 1,200 mg of S-adenosylmethionine (SAMe) or 1,200 mg of ibuprofen for four weeks. Morning stiffness, pain at rest, pain on motion, crepitus, swelling, and limitation of motion of the affected joints were assessed before and after treatment. The total score obtained by the evaluation of all the individual clinical parameters improved to the same extent in patients treated with SAMe or ibuprofen. Both treatments were well tolerated and no patient from either group withdrew from the study.

PMID:
3318445
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center