We analyzed group B Streptococcus (GBS) neonatal invasive infections reported during 2007-2019 in France. The hypervirulent clonal complex (CC) 17 GBS was responsible for 66% (827/1,262) of cases. The role of CC17 GBS increased over time (p for trend = 0.0001), together with the emergence of a multidrug-resistant CC17 GBS sublineage.
Keywords: France; GBS; Streptococcus agalactiae; antimicrobial resistance; bacteria; early-onset disease; group B Streptococcus; hypervirulent CC17 clone; late-onset disease; neonatal infections.