Format

Send to

Choose Destination
Neurology. 1988 Jul;38(7):1056-60.

Creutzfeldt-Jakob disease without periodic sharp wave complexes: a clinical, electroencephalographic, and pathologic study.

Author information

1
Department of Clinical Neurological Sciences, University of Western Ontario, London, Canada.

Abstract

A comparison of clinical, EEG, and pathologic features was carried out on all cases of autopsy-proven Creutzfeldt-Jakob disease (CJD) studied over the last 10 years. Periodic sharp wave complexes (PSWCs) were present in three but absent in seven patients. Myoclonus was documented in two of the three with and in only one of the seven without PSWCs. The three with PSWCs had severe neocortical and at least mild thalamic involvement; those without PSWCs had more variable disease topography. The diagnosis of CJD should not be rejected if PSWCs are absent.

PMID:
3290701
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center