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Nature. 1988 Apr 28;332(6167):800-5.

A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides.

Author information

1
Department of Biochemistry, University of California, Berkeley 94720.

Abstract

Depletion of a subset of 70K stress proteins in yeast mutants shows that they are involved in the post-translational import of precursor polypeptides into both mitochondria and the lumen of the endoplasmic reticulum. The identification of such a basic function may explain the remarkable evolutionary conservation of the gene family encoding these proteins.

PMID:
3282178
DOI:
10.1038/332800a0
[Indexed for MEDLINE]

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