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Nature. 1988 Apr 14;332(6165):604-9.

Two-tiered regulation of spatially patterned engrailed gene expression during Drosophila embryogenesis.

Author information

1
Department of Biochemistry and Biophysics, UCSF School of Medicine 94143-0448.

Abstract

A regulatory cascade, initiated during the syncytial stage of embryogenesis, culminates in the striped pattern of engrailed gene expression at the cellular blastoderm stage. The early regulatory genes, for example the pair-rule genes, are expressed transiently and as their products decay a distinct regulatory programme involving segment polarity genes takes over. This late programme maintains and perhaps modifies the striped pattern of engrailed expression through interactions that may involve cell communication.

PMID:
3282172
PMCID:
PMC2753417
DOI:
10.1038/332604a0
[Indexed for MEDLINE]
Free PMC Article

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