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Arch Dermatol. 1988 Apr;124(4):564-6.

Congenital sensory neuropathy with anhidrosis.

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Department of Dermatology, Yokohama City University School of Medicine, Japan.


Congenital sensory neuropathy with anhidrosis (CSNA) is a well-defined entity among a group of sensory deficiency syndromes. Children with this genetic disease are insensitive to pain and temperature, do not sweat, and suffer from mental retardation. Self-mutilation may be severe and may lead to insoluble orthopedic problems. We treated a girl with CSNA, who was born to nonconsanguineous Japanese parents. This disease is important in the dermatological field, since the degree of anhidrosis and self-mutilation influence the prognosis of patients with CSNA.

[Indexed for MEDLINE]

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