Format

Send to

Choose Destination
FEBS Lett. 1988 Feb 8;228(1):172-4.

Limited proteolysis of actin by a specific bacterial protease.

Author information

1
Institute of Cytology, USSR Academy of Sciences, Leningrad.

Abstract

A 36 kDa fragment of rabbit skeletal muscle actin resistant to further proteolytic breakdown was obtained with a new bacterial protease. This fragment was the only cleavage product obtained from native actin whereas proteolysis of heat-inactivated actin was unlimited. The 36 kDa fragment failed to polymerize and to inhibit DNase I activity. Binding to DNase I protects actin against proteolysis by protease. The results on actin proteolysis by different proteases are compared.

PMID:
3277858
DOI:
10.1016/0014-5793(88)80610-0
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center