Identification of a Cluster of Extended-spectrum Beta-Lactamase-Producing Klebsiella pneumoniae Sequence Type 101 Isolated From Food and Humans

Lisandra Aguilar-Bultet; Claudia Bagutti; Adrian Egli; Monica Alt; Laura Maurer Pekerman; Ruth Schindler; Reto Furger; Lucas Eichenberger; Tim Roloff; Ingrid Steffen; Philipp Huebner; Tanja Stadler; Sarah Tschudin-Sutter

doi:10.1093/cid/ciaa1164

Identification of a Cluster of Extended-spectrum Beta-Lactamase-Producing Klebsiella pneumoniae Sequence Type 101 Isolated From Food and Humans

Clin Infect Dis. 2021 Jul 15;73(2):332-335. doi: 10.1093/cid/ciaa1164.

Authors

Lisandra Aguilar-Bultet¹, Claudia Bagutti², Adrian Egli^{3

4}, Monica Alt², Laura Maurer Pekerman¹, Ruth Schindler¹, Reto Furger², Lucas Eichenberger², Tim Roloff^{3

4

5}, Ingrid Steffen⁶, Philipp Huebner², Tanja Stadler^{5

7}, Sarah Tschudin-Sutter^{1

8}

Affiliations

¹ Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, University of Basel, Basel, Switzerland.
² State Laboratory Basel-City, Biosafety Laboratory, Basel, Switzerland.
³ Division of Clinical Bacteriology and Mycology, University Hospital Basel, Basel, Switzerland.
⁴ Applied Microbiology Research, Department of Biomedicine, University of Basel, Basel, Switzerland.
⁵ Swiss Institute of Bioinformatics, Lausanne, Switzerland.
⁶ Rothen Laboratory, Basel, Switzerland.
⁷ Department of Biosystems Science and Engineering, Eidgenössische Technische Hochschule (ETH) Zurich, Zurich, Switzerland.
⁸ Department of Clinical Research, University Hospital Basel, Basel, Switzerland.

Abstract

We report a cluster of extended-spectrum beta-lactamase (ESBL)-producing Klebsiella pneumoniae sequence type 101, derived from 1 poultry and 2 clinical samples collected within the setting of a prospective study designed to determine the diversity and migration of ESBL-producing Enterobacterales between humans, foodstuffs, and wastewater.

Trial registration: ClinicalTrials.gov NCT03465683.

Keywords: Klebsiella pneumoniae; ESBL; One Health; poultry; sequence type 101.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anti-Bacterial Agents / pharmacology
Escherichia coli
Humans
Klebsiella Infections* / epidemiology
Klebsiella pneumoniae* / genetics
Microbial Sensitivity Tests
Prospective Studies
beta-Lactamases / genetics

Substances

Anti-Bacterial Agents
beta-Lactamases

Associated data

ClinicalTrials.gov/NCT03465683