Coronavirus Disease 2019 Infection in Children with Pre-Existing Heart Disease

Megan Simpson; Catherine Collins; Dustin B Nash; Laurie E Panesar; Matthew E Oster

doi:10.1016/j.jpeds.2020.07.069

Coronavirus Disease 2019 Infection in Children with Pre-Existing Heart Disease

J Pediatr. 2020 Dec:227:302-307.e2. doi: 10.1016/j.jpeds.2020.07.069. Epub 2020 Jul 27.

Authors

Megan Simpson¹, Catherine Collins², Dustin B Nash³, Laurie E Panesar⁴, Matthew E Oster⁵

Affiliations

¹ Department of Pediatrics, Emory University School of Medicine, Atlanta, GA.
² Department of Cardiology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL.
³ Division of Cardiology, Children's Hospital of Philadelphia, Philadelphia; PA.
⁴ Department of Cardiology, Stony Brook Children's Hospital, Stony Brook, NY.
⁵ Department of Pediatrics, Emory University School of Medicine, Atlanta, GA; Sibley Heart Center Cardiology, Children's Healthcare of Atlanta, Atlanta, GA. Electronic address: osterm@kidsheart.com.

Abstract

We present 7 children with congenital heart disease and coronavirus disease 2019. Of these, 5 were younger than 1 year of age and 3 had atrioventricular canal defect and trisomy 21. All 7 developed acute decompensation, with 1 death in an 18-year-old with hypertrophic cardiomyopathy and other comorbidities.

Keywords: COVID-19; SARS-CoV-2; congenital heart disease; coronavirus disease 2019.

Publication types

Case Reports

MeSH terms

Adolescent
COVID-19 / complications
COVID-19 / diagnosis*
COVID-19 Testing
Fatal Outcome
Female
Heart Defects, Congenital / complications*
Humans
Infant
Male
Young Adult