Autophagy and Liver Diseases

Jia Fan; Yinghong Shi; Yuanfei Peng

doi:10.1007/978-981-15-4272-5_37

Autophagy and Liver Diseases

Adv Exp Med Biol. 2020:1207:497-528. doi: 10.1007/978-981-15-4272-5_37.

Authors

Jia Fan¹, Yinghong Shi², Yuanfei Peng²

Affiliations

¹ Zhongshan Hospital, Fudan University, 180 FengLin Road, Shanghai, China. fan.jia@zs-hosptal.sh.cn.
² Zhongshan Hospital, Fudan University, 180 FengLin Road, Shanghai, China.

PMID: 32671772
DOI: 10.1007/978-981-15-4272-5_37

Abstract

Autophagy plays an important role in the physiology and pathology of the liver. It is involved in the development of many liver diseases such as α-1-antitrypsin deficiency, chronic hepatitis virus infection, alcoholic liver disease, nonalcoholic fatty liver disease, and liver cancer. Autophagy has thus become a new target for the treatment of liver diseases. How to treat liver diseases by regulating autophagy has been a hot topic.

Keywords: Autophagy; Cancer; Liver disease.

Publication types

Review

MeSH terms

Autophagy* / drug effects
Hepatitis, Chronic
Humans
Liver Diseases* / drug therapy
Liver Diseases, Alcoholic
Liver Neoplasms
Non-alcoholic Fatty Liver Disease
alpha 1-Antitrypsin Deficiency