Demographics, comorbidities and outcomes in hospitalized Covid-19 patients in rural southwest Georgia

Ann Med. 2020 Nov;52(7):354-360. doi: 10.1080/07853890.2020.1791356. Epub 2020 Jul 13.

Abstract

Background: There is limited data on outcomes in patients with coronavirus disease 2019 (Covid-19) in rural United States (US). This study aimed to describe the demographics, and outcomes of hospitalized Covid-19 patients in rural Southwest Georgia.

Methods: Using electronic medical records, we analyzed data from all hospitalized Covid-19 patients who either died or survived to discharge between 2 March 2020 and 6 May 2020.

Results: Of the 522 patients, 92 died in hospital (17.6%). Median age was 63 years, 58% were females, and 87% African-Americans. Hypertension (79.7%), obesity (66.5%) and diabetes mellitus (42.3%) were the most common comorbidities. Males had higher overall mortality compared to females (23 v 13.8%). Immunosuppression [odds ratio (OR) 3.6; (confidence interval (CI): 1.52-8.47, p=.003)], hypertension (OR 3.36; CI:1.3-8.6, p=.01), age ≥65 years (OR 3.1; CI:1.7-5.6, p<.001) and morbid obesity (OR 2.29; CI:1.11-4.69, p=.02), were independent predictors of in-hospital mortality. Female gender was an independent predictor of decreased in-hospital mortality. Mortality in intubated patients was 67%. Mortality was 8.9% in <50 years, compared to 20% in ≥50 years.

Conclusions: Immunosuppression, hypertension, age ≥ 65 years and morbid obesity were independent predictors of mortality, whereas female gender was protective for mortality in hospitalized Covid-19 patients in rural Southwest Georgia. KEY MESSAGES Patients hospitalized with Covid-19 in rural US have higher comorbidity burden. Immunosuppression, hypertension, age ≥ 65 years and morbid obesity are independent predictors of increased mortality. Female gender is an independent predictor of reduced mortality.

Keywords: Covid-19; baseline characteristics; demographics; outcomes; rural US.

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Black or African American / statistics & numerical data
  • COVID-19
  • Child
  • Child, Preschool
  • Comorbidity
  • Coronavirus Infections / epidemiology*
  • Coronavirus Infections / mortality
  • Female
  • Georgia / epidemiology
  • Hospital Mortality*
  • Hospitalization / statistics & numerical data*
  • Humans
  • Hypertension / epidemiology
  • Immunocompromised Host
  • Infant
  • Male
  • Middle Aged
  • Pandemics
  • Pneumonia, Viral / epidemiology*
  • Pneumonia, Viral / mortality
  • Retrospective Studies
  • Risk Factors
  • Rural Population / statistics & numerical data*
  • Sex Factors
  • Young Adult