Liver necrosis following cholecystectomy in sickle cell disease

Clin Case Rep. 2020 Mar 31;8(6):1114-1115. doi: 10.1002/ccr3.2820. eCollection 2020 Jun.

Abstract

Postoperative vaso-occlusive disease may be a life-threatening condition in patients affected by sickle cell disease, necessitating sometimes liver transplantation. After laparoscopic cholecystectomy, liver necrosis is usually secondary to intraoperative vascular injury. In this patient, the vaso-occlusive crisis mimicked a vascular injury with segmental postoperative necrosis.

Keywords: cholecystectomy; liver failure; liver necrosis; liver surgery; sickle cell disease.