Format

Send to

Choose Destination
See comment in PubMed Commons below
Ann Clin Biochem. 1988 Nov;25 ( Pt 6):634-7.

Variability of capillary plasma glucose in healthy individuals in repeated 75 g oral glucose tolerance tests.

Author information

1
Department of Biochemical Medicine, Ninewells Hospital and Medical School, Dundee, Scotland.

Abstract

A series of ten 75 g oral glucose tolerance tests was carried out on each of 14 apparently healthy subjects. The analytical, intra-individual and interindividual components of variation were calculated by nested ANOVA following duplicate analyses of capillary plasma glucose under optimal conditions. The analyses met the objectively set analytical goal of CV less than or equal to 2.2%. There was considerable intra-individual variation, but no subject was ever classified as diabetic or having impaired glucose tolerance. Recent criteria for interpretation of results must be used since conventional population-based reference values are not adequate. Serial results from an individual must differ by more than 0.7 mmol/L for fasting specimens and at least 1.6 mmol/L for other specimens for a statistically significant (P less than or equal to 0.05) change to have occurred.

PMID:
3254103
DOI:
10.1177/000456328802500606
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Atypon
    Loading ...
    Support Center