Correlation between Ivacaftor-induced CFTR Activation in Airway Epithelial Cells and Improved Lung Function: A Proof-of-Concept Study

Ann Am Thorac Soc. 2020 Aug;17(8):1024-1027. doi: 10.1513/AnnalsATS.202001-082RL.
No abstract available

Publication types

  • Letter

MeSH terms

  • Aminophenols / therapeutic use*
  • Cystic Fibrosis / drug therapy*
  • Cystic Fibrosis / physiopathology
  • Cystic Fibrosis Transmembrane Conductance Regulator / agonists
  • Epithelial Cells / drug effects*
  • Humans
  • Lung / drug effects*
  • Lung / physiopathology
  • Proof of Concept Study
  • Quinolones / therapeutic use*

Substances

  • Aminophenols
  • Quinolones
  • Cystic Fibrosis Transmembrane Conductance Regulator
  • ivacaftor