Effect of dried garlic on blood coagulation, fibrinolysis, platelet aggregation and serum cholesterol levels in patients with hyperlipoproteinemia

Atherosclerosis. 1988 Dec;74(3):247-9. doi: 10.1016/0021-9150(88)90244-4.

Abstract

The effects of intake of dried garlic on blood coagulation, fibrinolysis, platelet aggregation, serum cholesterol levels, and blood pressure were studied in 20 patients with hyperlipoproteinemia over a period of four weeks. Fibrinogen and fibrinopeptide A significantly decreased by 10%. Streptokinase activated plasminogen and fibrinopeptide B beta 15-42 significantly increased by about 10%. Serum cholesterol levels significantly decreased by 10%. Systolic and diastolic blood pressure decreased. ADP and collagen induced platelet aggregation were not influenced.

MeSH terms

  • Adult
  • Aged
  • Blood Coagulation*
  • Cholesterol / blood*
  • Fibrinolysis*
  • Food Preservation
  • Garlic*
  • Humans
  • Hyperlipoproteinemias / blood*
  • Middle Aged
  • Plants, Medicinal*
  • Platelet Aggregation*

Substances

  • Cholesterol