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Am J Med Genet. 1988 Dec;31(4):793-8.

Greig cephalopolysyndactyly syndrome: a possible mouse homologue (Xt-extra toes).

Author information

1
Kennedy Galton Centre, Northwick Park Hospital, Harrow, England.

Abstract

Greig cephalopolysyndactyly syndrome is an autosomal dominant form of complex polydactyly in man. Attention is called to the evidence that, on both morphological and comparative gene mapping grounds, this defect is homologous to Xt-extra toes in the mouse. The pattern of polydactyly in both species is very similar. In addition, both conditions probably map close to the T-cell receptor gamma polypeptide at 13 A2-3 in mouse and 7p15 in humans.

PMID:
3239570
DOI:
10.1002/ajmg.1320310411
[Indexed for MEDLINE]

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