An Up-to-Date Review on Bio-Resource Therapeutics Effective against Bacterial Species Frequently Associated with Chronic Sinusitis and Tonsillitis

Curr Med Chem. 2020;27(41):6892-6909. doi: 10.2174/0929867327666200505093143.

Abstract

Upper respiratory tract infections include inflammations of the nose, sinuses (sinusitis), pharynx (tonsillitis, pharyngitis) and larynx (laryngitis) with bacteria or viruses as the main cause of these conditions. Due to their repetitive nature, chronic respiratory infections represent a global problem which is often a result of improper treatment. If not treated adequately, these conditions may have serious consequences. On the other hand, mis - and overuse of antibiotics has reduced their efficiency and accelerated the development of resistant bacterial strains, which further complicates the treatment of infections. This literature review will focus on current knowledge regarding medicinal plants and mushrooms which have been traditionally used in the treatment of infections caused by chronic sinusitis and tonsillitis commonly linked to bacteria - Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, Fusobacterium nucleatum, Haemophilus influenzae and Moraxella catarrhalis. The present literature overview might be considered as a starting point for the development of novel, natural antimicrobial products with potential practical use in the treatment of chronic tonsillitis and sinusitis.

Keywords: Rhinosinusitis; extract; medicinal plants; mushrooms; respiratory tract; therapeutics.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Bacterial Infections / drug therapy*
  • Biological Products / therapeutic use*
  • Humans
  • Pharyngitis* / drug therapy
  • Pharyngitis* / microbiology
  • Sinusitis* / drug therapy
  • Sinusitis* / microbiology
  • Tonsillitis* / drug therapy
  • Tonsillitis* / microbiology

Substances

  • Anti-Bacterial Agents
  • Biological Products