Hendersonula toruloidea infection in Thailand

Int J Dermatol. 1988 Jul-Aug;27(6):391-5. doi: 10.1111/j.1365-4362.1988.tb02384.x.

Abstract

Hendersonula toruloidea infection is present in Thailand, where the clinical picture of tinea pedis is scales 61%, erythema 22%, maceration 10.8%, and hyperkeratosis 9%. The diagnosis was confirmed by repeated isolation of H. toruloidea. The slow-growing type was found more often than the fast-growing in the ratio of 2.8:1. In patients with H. toruloidea infection, skin test with Hs antigen of 1:10 was positive. Griseofulvin sensitivity test revealed that the MIC of 20 cultures was more than 100 micrograms/ml. Only 2 out of 93 cases (0.02%) were cured with half-strength Whitfield ointment for 4 months. Pathomechanism of the infection is being studied.

MeSH terms

  • Griseofulvin / therapeutic use
  • Humans
  • Keratosis / diagnosis
  • Mitosporic Fungi / isolation & purification*
  • Retrospective Studies
  • Skin Tests
  • Thailand
  • Tinea Pedis / diagnosis
  • Tinea Pedis / drug therapy
  • Tinea Pedis / microbiology*
  • Tinea Pedis / pathology

Substances

  • Griseofulvin