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Am J Trop Med Hyg. 2020 Mar 23. doi: 10.4269/ajtmh.19-0348. [Epub ahead of print]

Pregnancy and Chagas Disease: Benznidazole's Impact on Pregnancy and Newborns: A Report of Four Cases.

Author information

1
Hospital Universitario Virgen de la Arrixaca, Murcia, Spain.
2
Universidad de Murcia, Murcia, Spain.

Abstract

In recent decades and because of migration, Chagas disease has become a global public health problem. A significant focus has been placed on pregnant women who can transmit the disease to their offspring. Here, we report four cases of women who did not know that they were pregnant while they were being treated with benznidazole. A diagnosis was established according to serology and Trypanosoma cruzi PCR-standardized tests. Treatment was discontinued when pregnancy was confirmed, and a thorough follow-up was carried out. Although each case was different, none of the mothers developed health problems during pregnancy, and their newborns were delivered without any teratogenic effects.

PMID:
32207404
DOI:
10.4269/ajtmh.19-0348

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