Epidemiological features of rosacea in Changsha, China: A population-based, cross-sectional study

J Dermatol. 2020 May;47(5):497-502. doi: 10.1111/1346-8138.15301. Epub 2020 Mar 24.

Abstract

Rosacea is a common chronic skin disorder of unknown etiology. While population prevalence rates range 0.2-22% in Europe and North America, prevalence in China is currently undetermined. We conducted a large population-based case-control study to determine the present epidemiological status of rosacea in China, involving 10 095 participants aged 0-100 years (mean age, 35.5 ± 19.1; 50.5% female). A census of rosacea among 15 communities in Changsha in south central China was conducted with skin examination by board-certified dermatologists. Rosacea was observed in 3.48% (95% confidence interval, 3.13-3.85%) of the study population. Subtype distribution was erythematotelangiectatic in 47.6%, papulopustular in 35.0% and phymatous in 17.4%. Family history was noted in 37.8% and ocular symptoms in 31.3%. Associations with rosacea were observed for melasma, hypertension, hyperthyroidism and breast cancer in females (P < 0.05), and also for hyperthyroidism and peptic ulcers in males (P < 0.05). Our results provide baseline information about epidemiological aspects of rosacea in China.

Keywords: China; cross-sectional study; prevalence; relevant factors; rosacea.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Breast Neoplasms / epidemiology
  • Case-Control Studies
  • Child
  • Child, Preschool
  • China / epidemiology
  • Cross-Sectional Studies
  • Female
  • Humans
  • Hypertension / epidemiology
  • Hyperthyroidism / epidemiology
  • Infant
  • Infant, Newborn
  • Male
  • Melanosis / epidemiology
  • Middle Aged
  • Peptic Ulcer / epidemiology
  • Prevalence
  • Risk Factors
  • Rosacea / epidemiology*
  • Sex Factors
  • Young Adult