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Acad Pathol. 2020 Mar 17;7:2374289520909497. doi: 10.1177/2374289520909497. eCollection 2020 Jan-Dec.

Educational Case: Yolk Sac (Endodermal Sinus) Tumor of the Ovary.

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Department of Pathology and Laboratory Medicine, Northshore University Health System, Evanston, IL, USA.


The following fictional case is intended as a learning tool within the Pathology Competencies for Medical Education (PCME), a set of national standards for teaching pathology. These are divided into three basic competencies: Disease Mechanisms and Processes, Organ System Pathology, and Diagnostic Medicine and Therapeutic Pathology. For additional information, and a full list of learning objectives for all three competencies, see


Schiller-Duval body; endodermal sinus tumor; female reproductive; organ system pathology; ovarian neoplasia; pathology competencies; yolk sac tumor

Conflict of interest statement

Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

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