Testing the carbohydrate-insulin model in mice: The importance of distinguishing primary hyperinsulinemia from insulin resistance and metabolic dysfunction
Mol Metab. 2020 May:35:100960.
doi: 10.1016/j.molmet.2020.02.003.
Epub 2020 Feb 12.
1 New Balance Foundation Obesity Prevention Center, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA. Electronic address: david.ludwig@childrens.harvard.edu.
2 New Balance Foundation Obesity Prevention Center, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA.
3 Metabolism Research Lab, Department of Physiology and Developmental Biology, Brigham Young University, Provo, UT, USA.
4 Diabetes Research Group, Life Sciences Institute, Department of Cellular and Physiological Sciences, University of British Columbia, Institute for Personalized Therapeutic Nutrition, Vancouver, BC, Canada.