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IgG, IgM and IgA in the serum of cattle naturally infected with Mycobacterium paratuberculosis.

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Department of Epidemiology and Preventive Medicine, University of California, Davis 95616.


Serum IgG, IgM and IgA antibody response in 20 cattle naturally infected with Mycobacterium paratuberculosis and in 15 non-infected cattle were measured by enzyme-linked immunosorbent assay. A strong IgG response was detected in 16 (80%) of the infected animals. Diagnostic levels of IgM were detectable in all of the infected animals as well as in 8 (53%) of the non-infected animals. Animals with paratuberculosis had a very weak specific serum IgA response and this appears to be of little value in detection of infection in these animals.

[Indexed for MEDLINE]

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