1 Interventional Cardiology Unit, Cardiothoracic and Vascular Surgery Department, IRCCS Ospedale San Raffaele, Milan, Italy.
2 Interventional Cardiology Unit, Santa Maria University Hospital, Terni, Italy.
3 Unit of Internal Medicine, University Hospital, Terni, Italy.
4 Department of Medicine, University of Perugia, Perugia, Italy.
5 The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA - lorenzo.azzalini@mountsinai.org.