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Laryngoscope Investig Otolaryngol. 2019 Dec 23;5(1):145-151. doi: 10.1002/lio2.341. eCollection 2020 Feb.

Contemporary techniques in human otopathology and promise for the future.

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Otopathology Laboratory, Department of Otolaryngology Head and Neck Surgery, Massachusetts Eye and Ear Harvard Medical School Boston Massachusetts.


Contemporary histopathology of the ear is based on an evolution of equipment and histological techniques over the last 500 years, including the invention of the light microscope and protocols for fixation, embedment, sectioning, and staining of tissue samples, and visual documentation of findings. Several recent techniques which can be utilized in otopathology hold promise for significant improvement in methods and a better understanding of pathologic processes in diseases of the ear.


balance disorders; deafness; ear; histopathology; human; temporal bone

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No conflicts of interest were identified.

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