Severity of Cerebral Palsy-The Impact of Associated Impairments

Neuropediatrics. 2020 Apr;51(2):120-128. doi: 10.1055/s-0040-1701669. Epub 2020 Mar 2.

Abstract

Objective: This article describes associated impairments in children with cerebral palsy (CP) and its subtypes.

Method: Children born between 1990 and 2006 recorded in the Surveillance of Cerebral Palsy in Europe common database were studied. An "impairment index" characterized severity of impairments and their combinations.

Results: Amongst the 11,015 children analyzed, 56% (n = 5,968) could walk unaided, 54% (4,972) had normal or near-normal intellect (intelligence quotient ≥ 70). Except for ataxic CP, associated impairments were less frequent when walking ability was preserved. The impairment index was low (walking unaided and normal or near-normal intellect) in 30% of cases; 54% (n = 1,637) in unilateral spastic, 24% (n = 79) in ataxic, 18% (n = 913) in bilateral spastic, and 7% (n = 50) in dyskinetic CP. Around 40% had a high impairment index (inability to walk and/or severe intellectual impairment ± additional impairments)-highest in dyskinetic (77%, n = 549) and bilateral spastic CP (54%, n = 2,680). The impairment index varied little in birth weight and gestational age groups. However, significantly fewer cases in the birth weight group ≤ 1,000 g or gestational age group ≤ 27 weeks had a low impairment index compared to the other birth weight and gestational age groups (23 and 24% vs. between 27 and 32%).

Conclusion: Thirty percent of the children with CP had a low impairment index (they were able to walk unaided and had a normal or near-normal intellect). Severity in CP was strongly associated to subtype, whereas the association was weak with birth weight or gestational age.

MeSH terms

  • Ataxia / epidemiology
  • Ataxia / etiology
  • Ataxia / physiopathology*
  • Birth Weight
  • Cerebral Palsy / classification
  • Cerebral Palsy / complications
  • Cerebral Palsy / epidemiology
  • Cerebral Palsy / physiopathology*
  • Child
  • Comorbidity
  • Databases, Factual
  • Dyskinesias / epidemiology
  • Dyskinesias / etiology
  • Dyskinesias / physiopathology*
  • Europe / epidemiology
  • Gestational Age
  • Hearing Loss / epidemiology
  • Hearing Loss / etiology
  • Hearing Loss / physiopathology*
  • Humans
  • Intellectual Disability / epidemiology
  • Intellectual Disability / etiology
  • Intellectual Disability / physiopathology*
  • Mobility Limitation*
  • Muscle Spasticity / epidemiology
  • Muscle Spasticity / etiology
  • Muscle Spasticity / physiopathology*
  • Registries* / statistics & numerical data
  • Severity of Illness Index*
  • Vision Disorders / epidemiology
  • Vision Disorders / etiology
  • Vision Disorders / physiopathology*