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Demyelinating Diseases of the CNS (Brain and Spine).

Authors

Barkhof F4,5, Koeller KK6.

Editors

In: Hodler J1, Kubik-Huch RA2, von Schulthess GK3, editors.

Source

Diseases of the Brain, Head and Neck, Spine 2020–2023: Diagnostic Imaging [Internet]. Cham (CH): Springer; 2020. Chapter 13.
IDKD Springer Series.
2020 Feb 15.

Author information

1
Department of Radiology, University Hospital of Zürich, Zürich, Switzerland
2
Department of Radiology, Kantonsspital Baden, Baden, Aargau, Switzerland
3
Nuclear Medicine, University Hospital of Zürich, Zürich, Switzerland
4
Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, The Netherlands
5
UCL Institutes of Neurology and Healthcare Engineering, London, UK
6
Section of Neuroradiology, Department of Radiology, Mayo Clinic, Rochester, MN, USA

Excerpt

Multiple sclerosis (MS) is the most important idiopathic inflammatory disorders that affects both the brain and spine. Dissemination in space and time on MRI is not limited to MS and can occur in neuromyelitis optica (NMO) and a series of other inflammatory disorders. Spinal cord imaging is an important element of MS (differential) diagnosis and especially relevant in case of possible age-related vasculo-ischemic brain white matter lesions; a negative scan will help to rule out MS. Increasingly, MRI is used to monitor treatment and their complications such as progressive multifocal leukoencephalopathy (PML).

Copyright 2020, The Author(s).

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