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Clin Infect Dis. 2020 Feb 29. pii: ciaa199. doi: 10.1093/cid/ciaa199. [Epub ahead of print]

Clinical Characteristics of Imported Cases of COVID-19 in Jiangsu Province: A Multicenter Descriptive Study.

Author information

1
State Key Laboratory for the Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
2
Department of Laboratory Medicine, The First People's Hospital of Yancheng City, Yancheng, China.
3
Department of Laboratory Medicine, The Fifth People's Hospital of Wuxi, Affiliated to Jiangnan University, Wuxi, China.
4
Department of Respiration, The Fifth People's Hospital of Wuxi, Affiliated to Jiangnan University, Wuxi, China.
5
Department of Infectious Disease, The First People's Hospital of Yancheng City, Yancheng, China.
6
Department of Infectious Disease, The second People's Hospital of Yancheng City, Yancheng, China.
7
Department of Preventive Medicine and Public Health Laboratory Sciences, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, China.
8
Department of Laboratory Medicine, The second People's Hospital of Yancheng City, Yancheng, China.
9
Department of Laboratory Medicine, The Central Blood Station of Yancheng City, Yancheng, Jiangsu, China.
10
Zhejiang Provincial Key Laboratory for Diagnosis and Treatment of Aging and Physic-chemical Injury Diseases, Hangzhou, China.

Abstract

BACKGROUND:

We aimed to report the clinical characteristics of imported coronavirus disease-19 (COVID-19) in Jiangsu Province.

METHODS:

We retrospectively investigated the clinical, imaging, and laboratory characteristics of confirmed cases of COVID-19 with WHO interim guidance in three Grade ⅢA hospitals of Jiangsu from Jan 22 to Feb 14, 2020. Real time RT-PCR was used to detect the new coronavirus in respiratory samples.

RESULTS:

Of the 80 patients infected with COVID-19, 41 patients were female, with a median age of 46.1 years. Except for 3 severe patients, the rest of the 77 patients exhibited mild or moderate symptoms. 9 patients were unconfirmed until a third-time nucleic acid test. 38 cases had a history of chronic diseases. The main clinical manifestations of the patients were fever and cough, which accounted for 63 cases (78.75%) and 51 cases (-63.75%) respectively. Only 3 patients (3.75%) showed liver dysfunction. Imaging examination showed that 55 patients (-68.75%) showed abnormal, 25 cases (31.25%) had no abnormal density shadow in the parenchyma of both lungs. Up to now, 21 cases were discharged from the hospital, and no patient died. The average length of stay for discharged patients was 8 days.

CONCLUSIONS:

Compared with the cases in Wuhan, the cases in Jiangsu exhibited mild or moderate symptoms and no obvious gender susceptivity. The proportion of patients having liver dysfunction and abnormal CT imaging was relatively lower than that of Wuhan. Notably, infected patients may be falsely excluded based on two consecutively negative respiratory pathogenic nucleic acid test results.

KEYWORDS:

Coronavirus disease-19 (COVID-19); clinical characteristics; imported cases; pneumonia

PMID:
32109279
DOI:
10.1093/cid/ciaa199

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