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Indian J Pathol Microbiol. 2020 Feb;63(Supplement):S50-S52. doi: 10.4103/IJPM.IJPM_427_18.

Rapidly progressing malignant phyllodes tumor of the prostate with normal prostate-specific antigen levels: A case report.

Author information

1
Department of Pathology, Jiujiang University Clinical Medical College, Jiujiang, China.
2
Department of Neurology, Jiujiang University Clinical Medical College, Jiujiang, China.

Abstract

Malignant phyllodes tumor of the prostate is a very rare entity. Here, we describe a 51-year-old patient with a malignant phyllodes tumor of the prostate with a poor prognosis and normal prostate-specific antigen levels. Digital rectal examination revealed a hard, nodular mass in the prostate, and magnetic resonance imaging exhibited a cystic mass measuring 8.7 cm × 7.0 cm × 6.7 cm. Immunohistochemical staining showed that the epithelial components were positive for CK8/18 and cytokeratin AE1/AE3; the atypical stromal cells were positive for CD34 and vimentin. Histological analysis resulted in a diagnosis of malignant phyllodes tumor of the prostate. Radical surgery was the treatment of choice. However, tumor recurrence was identified 6 months after the surgery, and the patient died 10 months after the surgery.

KEYWORDS:

Immunohistochemical analysis; malignant phyllodes tumor; prostate; prostate-specific antigen

PMID:
32108628
DOI:
10.4103/IJPM.IJPM_427_18
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