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Haematologica. 2020 Feb 27. pii: haematol.2020.248385. doi: 10.3324/haematol.2020.248385. [Epub ahead of print]

FcγRI and FcγRIII on splenic macrophages mediate phagocytosis of anti-glycoprotein IIb/IIIa autoantibody-opsonized platelets in immune thrombocytopenia.

Author information

1
Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada.
2
University of Rochester Medical Center, Rochester, NY, United States.
3
Justus Liebig University Giessen, Giessen, Germany.
4
Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Amsterdam.
5
Laboratory Medicine Program, University Health Network, Toronto, ON, Canada.
6
Sunnybrook Health Sciences Centre, Toronto, ON, Canada.
7
Centre for Innovation, Canadian Blood Services, Ottawa, ON, Canada.
8
Division of Hematology and Transfusion Medicine, Lund University, Lund, Sweden.
9
Centre for Innovation, Canadian Blood Services, Ottawa, ON, Canada; lazarusa@smh.ca.

KEYWORDS:

Granulocytes, Monocytes, Macrophages; Immune Thrombocytopenic Purpura; Phagocytosis; Platelets

PMID:
32107327
DOI:
10.3324/haematol.2020.248385
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