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Nutrients. 2020 Feb 21;12(2). pii: E566. doi: 10.3390/nu12020566.

Direct-to-Consumer Nutrigenetics Testing: An Overview.

Author information

1
Department of Biomedical Sciences, University of Sassari, Viale San Pietro 43/b, 07100 Sassari, Italy.
2
Institute for Genetic and Biomedical Research, National Research Council, traversa La Crucca 3, 07100 Sassari, Italy.
3
Department of Chemistry and Pharmacy, University of Sassari, Via Muroni 23/A, 07100 Sassari, Italy.
4
Institute for Genetic and Biomedical Research, National Research Council, SS 554 Km 4,500, Monserrato, 09042 Cagliari, Italy.
5
Laboratory of Molecular Biology and Stem Cell Engineering, National Institute of Biostructures and Biosystems-Eldor Lab, Innovation Accelerator, CNR, Via Piero Gobetti 101, 40129 Bologna, Italy.
6
Center for Developmental Biology and Reprogramming-CEDEBIOR, Department of Biomedical Sciences, University of Sassari, Viale San Pietro 43/b, 07100 Sassari, Italy.

Abstract

At present, specialized companies offering genetic testing services without the involvement of clinicians are growing; this development is a direct consequence of the significant decrease in genotyping and sequencing costs. Online companies offer predictions about the risk of developing complex diseases during one's life course, and they offer suggestions for personal lifestyle. Several companies have been created that provide nutrigenetics services; these companies suggest dietary indications-a central issue in the prevention and etiopathogenesis of specific diseases-based on one's personal genetic background. Dietary patterns are defined on the basis of a limited set of genetic markers. In this article, we analyze the online nutrigenetics services offered by 45 companies worldwide, to obtain an overall picture of the costs, the types of nutritional traits considered and the level of scientific precision of the services proposed. Our analysis clearly highlights the need for specific guidelines, in order to ensure a set of minimum quality standards for the nutrigenetics services offered to the customer.

KEYWORDS:

diet; direct-to-consumer genetic testing (DTC-GT); genetic; nutrigenetics; nutrigenomics; nutrition

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