Send to

Choose Destination
Nutrients. 2020 Feb 19;12(2). pii: E530. doi: 10.3390/nu12020530.

High Consumption of Soft Drinks Is Associated with an Increased Risk of Fracture: A 7-Year Follow-Up Study.

Chen L1,2,3,4, Liu R1,2,3,4, Zhao Y1,2,3,4, Shi Z5.

Author information

School of Public Health and Management, Chongqing Medical University, Chongqing 400016, China.
Research Center for Medicine and Social Development, Chongqing Medical University, Chongqing 400016, China.
The Innovation Center for Social Risk Governance in Health, Chongqing Medical University, Chongqing 400016, China.
Chongqing Key Laboratory of Child Nutrition and Health, Chongqing 400016, China.
Human Nutrition Department, College of Health Science, QU Health, Qatar University, Doha 2713, Qatar.


(1) Background: Fracture causes a substantial burden to society globally. Some studies have found that soft drinks consumption was associated with the risk of fractures. We aimed to assess the association in the Chinese population; (2) Methods: Data from 17,383 adults aged 20 to 75 years old attending the China Health and Nutrition Survey (CHNS) between 2004 and 2011 were analyzed. Soft drinks consumption and fracture occurrence were self-reported. The cross-sectional and longitudinal associations between soft drink and fracture was assessed using multivariable mixed-effect logistic regression and Cox regression; (3) Results: After adjusting for sociodemographic and lifestyle factors and dietary patterns, compared with those who did not consume soft drinks, participants with daily consumption of soft drinks had an odds ratio (95%CI) of 2.72 (95%CI: 1.45-5.09) for fracture. During a mean 5-year follow-up, there were 569 incident fracture cases. Compared with non-consumers, those with daily soft drinks consumption had a hazard ratio (95%CI) of 4.69 (95%CI: 2.80-7.88) for incident fracture; (4) Conclusions: Soft drinks consumption is directly associated with the risk of fracture. Reducing soft drinks consumption should be considered as an important strategy for individual and population levels to maintain bone health.


China Health and Nutrition Survey; epidemiology; fracture; longitudinal study; soft drinks

Supplemental Content

Full text links

Icon for Multidisciplinary Digital Publishing Institute (MDPI) Icon for PubMed Central
Loading ...
Support Center