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Infection. 2020 Feb 18. doi: 10.1007/s15010-020-01401-y. [Epub ahead of print]

2019 Novel coronavirus: where we are and what we know.

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Institute of Allergy and Immunology, School of Medicine, Shenzhen University, Shenzhen, China.
Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, USA.
Institute of Medical Physics, University of Sydney, Sydney, Australia.
Discipline of Child and Adolescence Health, The Faculty of Medicine and Health, University of Sydney, Sydney, Australia.


There is a current worldwide outbreak of a new type of coronavirus (2019-nCoV), which originated from Wuhan in China and has now spread to 17 other countries. Governments are under increased pressure to stop the outbreak spiraling into a global health emergency. At this stage, preparedness, transparency, and sharing of information are crucial to risk assessments and beginning outbreak control activities. This information should include reports from outbreak sites and from laboratories supporting the investigation. This paper aggregates and consolidates the virology, epidemiology, clinical management strategies from both English and Chinese literature, official news channels, and other official government documents. In addition, by fitting the number of infections with a single-term exponential model, we report that the infection is spreading at an exponential rate, with a doubling period of 1.8 days.


2019-nCoV; COVID-19; China; Clinical guideline; Coronavirus; Epidemiology; Literature review; Literature survey; Novel coronavirus; Review; Virology; Wuhan


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