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J Med Virol. 2020 May;92(5):476-478. doi: 10.1002/jmv.25708. Epub 2020 Feb 24.

Does SARS-CoV-2 has a longer incubation period than SARS and MERS?

Jiang X1,2, Rayner S3,4,5, Luo MH1,2,5,6,7.

Author information

1
The Joint Center of Translational Precision Medicine Guangzhou Institute of Pediatrics, Guangzhou Women and Children Medical Center, Guangzhou, China.
2
The Joint Center of Translational Precision Medicine, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
3
Department of Medical Genetics, Oslo University Hospital and University of Oslo, Oslo, Norway.
4
Hybrid Technology Hub-Centre of Excellence, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
5
Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
6
State Key Laboratory of Virology, CAS Center for Excellence in Brain Science and Intelligence Technology (CEBSIT), Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
7
University of Chinese Academy of Sciences, Beijing, China.

Abstract

The outbreak of a novel coronavirus (SARS-CoV-2) since December 2019 in Wuhan, the major transportation hub in central China, became an emergency of major international concern. While several etiological studies have begun to reveal the specific biological features of this virus, the epidemic characteristics need to be elucidated. Notably, a long incubation time was reported to be associated with SARS-CoV-2 infection, leading to adjustments in screening and control policies. To avoid the risk of virus spread, all potentially exposed subjects are required to be isolated for 14 days, which is the longest predicted incubation time. However, based on our analysis of a larger dataset available so far, we find there is no observable difference between the incubation time for SARS-CoV-2, severe acute respiratory syndrome coronavirus (SARS-CoV), and middle east respiratory syndrome coronavirus (MERS-CoV), highlighting the need for larger and well-annotated datasets.

KEYWORDS:

coronavirus; incubation; local infection/replication/spread; pandemic; virulence

PMID:
32056235
DOI:
10.1002/jmv.25708
[Indexed for MEDLINE]

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