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Cell Host Microbe. 2020 Feb 12;27(2):163-165. doi: 10.1016/j.chom.2020.01.014.

Uncovering the Anti-Ebola Repertome.

Author information

1
Division of Virology, Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyo, Tokyo, Japan.
2
Division of Virology, Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyo, Tokyo, Japan; Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA; Department of Special Pathogens, International Research Center for Infectious Diseases, Institute of Medical Science, University of Tokyo, Tokyo, Japan. Electronic address: yoshihiro.kawaoka@wisc.edu.

Abstract

Ebolavirus disease is a global threat. In this issue, Khurana et al. reveal the antibody response against all ebolavirus proteins by analyzing longitudinal antibody repertoires of an Ebola survivor from disease onset. Antibodies against VP40 and GP are found to predominate and two protective antigenic sites in GP identified.

PMID:
32053784
DOI:
10.1016/j.chom.2020.01.014

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