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Klin Lab Diagn. 2019;64(12):730-735. doi: 10.18821/0869-2084-2019-64-12-730-735.

[Evaluation of hyperglycemia impact on outcomes of acute coronary syndrome in elderly and senile patients.]

[Article in Russian]

Author information

1
I.P. Pavlov First Saint-Petersburg State Medical University, 197022, St.Petersburg, Russian Federation.
2
St.Petersburg State Budgetary Healthcare Institution «City Multi-field hospital №2», 194354, St.Petersburg, Russian Federation.
3
St.Petersburg Institute of Bioregulation and Gerontology, 197110, St.Petersburg, Russia.
4
St. Petersburg State University, 199034, St.Petersburg, Russian Federation.

Abstract

Acute coronary syndrome (ACS) in elderly and senile patients has a number of features and requires special attention to providing medical care. These patients is associated with significant comorbidity and atypical symptoms in the course of the disease. Diabetes mellitus is a common background disease in patients with ACS.A retrospective cohort study was performed, 2945 patients with ACS were examined. Patients were divided into three age groups: group 1 - patients aged 18 to 63 years; group 2 - patients aged 64 to 75 years; group 3 - patients older than 75 years. Number of patients with glucose concentrations above 11.1 mmol/L is significantly higher in elderly and senile groups than in group of patients from 35 to 59 years old. The number of patients with impaired renal function after administration of a contrast medium in the study group with ACS increased with increasing age. Significant difference was revealed between the middle and senile age groups, as well as between the elderly and senile age groups. An increase in the relative number of patients with fatal outcomes in groups with a significant increase in glucose levels was revealed. The connection between the pathological level of glucose and repeated myocardial infarction is proved. Conclusion. The presented statistical picture suggests a particularly high risk of recurring cardiovascular events among patients with ACS and pathological glucose levels. The correlation between the number of deaths and glucose levels during the initial examination allows the use of glucose tests as an additional criterion in the stratification of risks and outcomes in patients with ACS.

KEYWORDS:

acute coronary syndrome; elderly and senile patients; glucose

Conflict of interest statement

The authors declare no conflict of interest.

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