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Anesth Essays Res. 2019 Oct-Dec;13(4):615-619. doi: 10.4103/aer.AER_122_19. Epub 2019 Dec 16.

Ultrasound-Guided Subclavian Perivascular Brachial Plexus Block Using 0.5% Bupivacaine with Dexmedetomidine as an Adjuvant: A Prospective Randomized Controlled Trial.

Author information

1
Department of Anaesthesia, Mediciti Institute of Medical Sciences, Hyderabad, Telangana, India.

Abstract

Background:

Ultrasound guidance has dramatically improved the accuracy of nerve localization, and various adjuvants prolong the block and extend analgesia.

Aims:

This study aimed to evaluate the effects of dexmedetomidine added to 0.5% bupivacaine on the onset and duration of motor and sensory blockade and the duration of analgesia.

Settings and Design:

This is a prospective, randomized double-blind, study.

Materials and Methods:

Sixty adult patients aged 20-60 years of either sex undergoing orthopedic procedures on the forearm were randomly allocated into two groups of thirty each: Group BS (bupivacaine + saline) and Group BD (bupivacaine + dexmedetomidine). All patients were administered subclavian perivascular brachial plexus block under ultrasound guidance. Group BS: Patients in this group were administered 20-mL 0.5% bupivacaine + 0.75-mL saline. Group BD: Patients in this group were administered 20-mL 0.5% bupivacaine + 0.75-mL dexmedetomidine (75 μg).

Statistical Analysis:

Statistical analysis was performed with IBM SPSS software Version 21.0. Quantitative data were expressed as mean ± standard deviation. Independent sample t-test was used for comparisons between the two groups. P < 0.05 was considered statistically significant.

Results:

Demographic data and surgical characteristics were similar in both groups. The onset times for sensory and motor blocks were statistically significantly shorter in Group BD compared to Group BS (P < 0.01), whereas the duration of blocks and analgesia were statistically significantly longer (P < 0.01) in Group BD.

Conclusion:

The addition of dexmedetomidine to 0.5% bupivacaine for supraclavicular brachial plexus block shortens the onset time and prolongs both the duration of the block and analgesia.

KEYWORDS:

Bupivacaine; dexmedetomidine; subclavian perivascular brachial plexus; ultrasound

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