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J Bone Jt Infect. 2019 Nov 7;4(6):280-284. doi: 10.7150/jbji.35424. eCollection 2019.

Humoral Factors From Musculoskeletal Polytrauma Patients Impair Antibacterial Responses Of Neutrophils In vitro.

Author information

1
AO Research Institute Davos, Davos, Switzerland.
2
Department of Orthopaedic and Trauma Surgery, University Hospital Basel, Switzerland.

Abstract

Polytrauma is associated with increased risk of sepsis, but the risk for implant infection is less clear. Neutrophil antibacterial responses are significantly reduced in polytrauma patients (n= 9, ISS≥15) for at least 5 days compared to healthy controls. Reduced neutrophil activity could influence implant infection in addition to sepsis.

KEYWORDS:

antibacterial activity; neutrophil; polytrauma

Conflict of interest statement

Competing Interests: The authors have declared that no competing interest exists.

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