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Cell Stem Cell. 2020 Jan 2;26(1):4-6. doi: 10.1016/j.stem.2019.12.003.

Organoids as Oracles for Precision Medicine in Rectal Cancer.

Author information

1
Department of Medicine, Division of Hematology, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.
2
Department of Medicine, Division of Hematology, Stanford University School of Medicine, Stanford, CA 94305, USA.
3
Department of Medicine, Division of Hematology, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address: cjkuo@stanford.edu.

Abstract

Two recent papers in Cell Stem Cell and Nature Medicine (Yao et al. [2019] and Ganesh et al. [2019]) demonstrate the successful use of rectal cancer patient-derived organoids to predict patient responses to neoadjuvant chemoradiation therapy, paving the way toward a new paradigm for precision medicine.

PMID:
31951587
DOI:
10.1016/j.stem.2019.12.003

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