Format

Send to

Choose Destination
Conf Proc IEEE Eng Med Biol Soc. 2019 Jul;2019:2964-2967. doi: 10.1109/EMBC.2019.8857298.

A Predictive Coding Model for Evoked and Spontaneous Pain Perception.

Abstract

Pain is a complex multidimensional experience, and pain perception is still incompletely understood. Here we combine animal behavior, electrophysiology, and computer modeling to dissect mechanisms of evoked and spontaneous pain. We record the local field potentials (LFPs) from the primary somatosensory cortex (S1) and anterior cingulate cortex (ACC) of freely behaving rats during pain episodes, and develop a predictive coding model to investigate the temporal coordination of oscillatory activity between the S1 and ACC. Our preliminary results from computational simulations support the experimental findings and provide new predictions.

PMID:
31946512
DOI:
10.1109/EMBC.2019.8857298

Supplemental Content

Full text links

Icon for IEEE Engineering in Medicine and Biology Society Icon for NYU School of Medicine
Loading ...
Support Center