Send to

Choose Destination
BMJ Open. 2020 Jan 9;10(1):e026560. doi: 10.1136/bmjopen-2018-026560.

Association between muscle strength and health-related quality of life in a Chinese rural elderly population: a cross-sectional study.

Author information

Institute of Geriatrics, Beijing Key Laboratory of Aging and Geriatrics, National Clinical Research Center for Geriatrics Disease, State Key Laboratory of Kidney Disease, the 2nd Medical Center, Chinese PLA General Hospital, Beijing, China.
Northern Military Area CDC, Shenyang, China.
The 2nd Medical Center, National Clinical Research Center for Geriatrics Disease, Chinese PLA General Hospital, Beijing, China.
Miyun County Hospital of Traditional Chinese Medicine, Beijing, China.
Department of Traditional Chinese Medicine and Acupuncture, The 2nd Medical Center, Chinese People's Liberation Army General Hospital, Beijing, China.
Contributed equally



To investigate the relationship between upper and lower limb muscle strength and the health-related quality of life (HRQoL) of a Chinese rural, elderly population.


A population-based, cross-sectional study.


Miyun, Beijing, China.


The participants of this study were 2083 (834 men and 1249 women) older adults from a rural area, (average age of ≥60 years), living in Miyun county, located on the outskirts of Beijing. Data were collected between May and October 2014. Handgrip strength and timed up and go tests (TUGT) were conducted to measure the muscle strength of their upper and lower limbs, respectively. The Euro Quality of Life (Euroqol) (EQ-5D)-Visual Analogue Scale was used to evaluate participants' HRQoL.


A significant association between handgrip strength and the EQ-5D index (β=0.015 per SD, 95% CI: 0.008 to 0.023, p<0.001) was discovered, following adjustments. The association between handgrip strength and the EQ-5D index in the ≥80 years group was found to be stronger than that of the 60-79 years group, following adjustment (β per SD: 0.013 vs 0.035). Similar results were observed when comparing the non-chronic disease group, in terms of TUGT time, against those with chronic diseases.


There was a significant relationship between muscle strength (measured via handgrip strength and TUGT time) and HRQoL (measured via EQ-5D index and VAS score) in the Chinese rural elderly population. Furthermore, this relationship was stronger in the older population (aged ≥80 years), and in those participants diagnosed with chronic diseases.


chinese elderly rural residents; handgrip strength; health related quality of life; timed up and go test

Free full text

Conflict of interest statement

Competing interests: We confirm that this manuscript contains original unpublished work and is not being submitted for publication elsewhere at the same time. This manuscript has been read and approved by all the authors; the requirements for authorship have been met; each author believes that the manuscript represents honest work.

Supplemental Content

Full text links

Icon for HighWire
Loading ...
Support Center