Format

Send to

Choose Destination
BMJ Case Rep. 2020 Jan 8;13(1). pii: e232844. doi: 10.1136/bcr-2019-232844.

Anaphylaxis to goat/sheep's milk in a 4-year-old boy tolerant to cow's milk.

Author information

1
Department of Pediatrics, Division of Allergy, Immunology and Dermatology, Montreal Children's Hospital, Montreal, Québec, Canada pasquale.mule2@mail.mcgill.ca.
2
Department of Pediatrics, Division of Allergy, Immunology and Dermatology, Montreal Children's Hospital, Montreal, Québec, Canada.
3
Department of Pediatrics, Division of Immunology and Allergy, Hospital for Sick Children, Toronto, Ontario, Canada.
4
Department of Pediatrics, Section of Allergy and Clinical Immunology, University of Manitoba, Winnipeg, Manitoba, Canada.
5
Department of Pediatrics, Division of Allergy and Immunology, The University of British Columbia, Vancouver, British Columbia, Canada.

Abstract

Immune-mediated reactions to dairy products may vary depending on the mammalian source. We present a case of anaphylaxis to goat/sheep's milk with tolerance to cow's milk. A 4-year-old boy of Eastern European descent presented with gastrointestinal and respiratory symptoms within minutes after eating a goat/sheep's milk-derived food product. The tryptase level measured 1 hour post initial symptoms and 1 month after the allergic reaction were 14.6 µg/L and 5.1 µg/L, respectively (norm: 0.0-13.5 µg/L), confirming the diagnosis of anaphylaxis. A skin prick test performed 1 month after the reaction was highly positive for goat/sheep's milk, but negative for cow's milk. Skin prick tests may establish a life-threatening goat/sheep's milk allergy. Goat/sheep's milk allergy should always be considered in cow's milk-tolerant patients who present with an allergic reaction to dairy products, or when undergoing/have completed of oral immunotherapy for cow's milk allergy.

KEYWORDS:

allergy, asthma; immunology

PMID:
31919067
DOI:
10.1136/bcr-2019-232844

Conflict of interest statement

Competing interests: None declared.

Supplemental Content

Full text links

Icon for HighWire
Loading ...
Support Center