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Front Physiol. 2019 Nov 26;10:1435. doi: 10.3389/fphys.2019.01435. eCollection 2019.

The Role of the Gut Microbiome on Skeletal Muscle Mass and Physical Function: 2019 Update.

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1
Nutrition, Exercise Physiology, and Sarcopenia Laboratory, Jean Mayer United States Department of Agriculture Human Nutrition Research Center (HNRCA), Tufts University, Boston, MA, United States.

Abstract

Within the past year, several studies have reported a positive role for the gut microbiome on the maintenance of skeletal muscle mass, evidence that contrasts previous reports of a negative role for the gut microbiome on the maintenance of whole body lean mass. The purpose of this mini-review is to clarify these seemingly discordant findings, and to review recently published studies that further elucidate the gut-muscle axis.

KEYWORDS:

endurance capacity; gut-muscle axis; microbiome; muscle strength; short chain fatty acid; skeletal muscle

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