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Anesth Pain Med. 2019 Oct 22;9(5):e92072. doi: 10.5812/aapm.92072. eCollection 2019 Oct.

Dose Ginger Have Preventative Effects on PONV-Related Eye Surgery? A Clinical Trial.

Author information

1
Department of Anesthesia, Iran University of Medical Sciences, Tehran, Iran.
2
Department of Molecular Biology, Iran University of Medical Sciences, Tehran, Iran.
3
Pain Research Center, Iran University of Medical Sciences, Tehran, Iran.
4
Mazandaran University of Medical Sciences, Sari, Iran.
5
Vocational Health College of Mardin Artuklu University, Mardin, Turkey.

Abstract

Background:

Postoperative nausea and vomiting (PONV) is considered a common complication of anesthesia, which, particularly in eye surgery, may exert pressure on stitches and open or leak the surgical wound, leading to bleeding.

Objectives:

We aimed to study the effect of ginger on PONV and changes in vital signs after eye surgery.

Methods:

In this triple-blind randomized controlled trial, 120 candidate patients for eye surgery were divided into group A (n = 40) and group B (n = 40). Patients in group A received the capsules of ginger 1 g while patients in group B received a placebo one hour before the procedure with 30 mL water. The incidence of nausea and the frequency of vomiting were evaluated at 0, 15, 30 minutes, and 2 hours after the operation. Also, the vital signs of the participants were recorded at certain times.

Results:

The results demonstrated a statistically significant difference in the frequency of nausea between group A and group B (P < 0.05). The severity of nausea was lower in group A than in group B immediately and 2 hours after recovery (P < 0.05). The incidence of vomiting was significantly lower in group A than in group B (P < 0.05). The vital signs were not significantly different between group A and group B (P > 0.05).

Conclusions:

Ginger was effective in the prevention of PONV after eye surgery but had no impact on vital signs. Hence, ginger is proposed to use as a low-cost, prophylactic measure for PONV reduction.

KEYWORDS:

Eye Surgery; Ginger; Nausea; PONV; Vomiting

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