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Asian J Transfus Sci. 2019 Jul-Dec;13(2):132-135. doi: 10.4103/ajts.AJTS_152_17. Epub 2019 Dec 3.

Deciphering a delayed hemolytic transfusion reactions nightmare - Case of Chido/Roger antibodies.

Author information

1
Department of Transfusion Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
2
Department of Nephrology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
3
Department of Transfusion Medicine, Bangalore Medical Services Trust, Rotary Bangalore TTK Blood Bank, Bengaluru, Karnataka, India.

Abstract

Antibodies against Rh (CEce) and Kidd (Jka and Jkb) system antigens are mostly implicated in delayed hemolytic transfusion reactions (DHTR), which is a potentially life-threatening complication observed in patients receiving chronic transfusions. Here, we are describing a case of Chido/Roger antibody which presented to our laboratory as DHTR. The clinical presentation and laboratory findings including the immunohematological workups with regard to the reaction are discussed, with a special emphasis on the benefit of identifying such an antibody and obtaining blood unit for transfusion supports the patient with respect to providing a compatible unit.

KEYWORDS:

Chido/roger antibody; delayed hemolytic transfusion reaction; red blood cell transfusion

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