Format

Send to

Choose Destination
J Nutr Health Aging. 2020;24(1):107-112. doi: 10.1007/s12603-019-1278-7.

Association between Depressive Symptoms and Supplemental intake of Calcium and Vitamin D in Older Adults.

Author information

1
Junfen Lin, Zhejiang Provincial Center for Disease Control and Prevention, 3399 Binsheng Road, Binjiang District, Hangzhou 310051, Zhejiang, China, zjlinjunfen@163.com, Tel: +86 57187115131, Fax: +86 0571 87115278.

Abstract

OBJECTIVES:

We explored the associations between depressive symptoms and supplemental calcium and vitamin D intake in older adults.

DESIGN:

This was a prospective cohort study.

PARTICIPANTS:

8,527 older adults aged ≥60 years from Zhejiang Major Public Health Surveillance Program (ZPHS) without depressive symptoms at baseline survey.

MEASUREMENTS:

Participants were divided into non-supplementation, calcium (Ca), vitamin D, and calcium plus vitamin D (CaD) groups based on their supplemental intake during the past year. Depressive symptoms were assessed using the Patient Health Questionnaire-9 (PHQ-9). Binary logistic regression analyses were performed to examine the association between depressive symptoms and supplemental intake.

RESULTS:

When compared to the non-supplementation group, the Ca group exhibited a significant odds ratio (OR) of 0.731 (95% CI: 0.552-0.967, P=0.028). After adjusting for age, sex, and Ca food sources, the OR was even smaller for the CaD group (OR: 0.326; 95% CI: 0.119-0.889, P=0.029). Additionally, our results indicated that taking Ca supplements ≥4 days/week yielded a significant OR of 0.690 (95% CI: 0.492-0.968) after full adjustment. Taking CaD supplements ≥4 days/week yielded a significant OR of 0.282 (95% CI: 0.089-0.898) after adjusting for age, sex, and Ca food sources.

CONCLUSIONS:

Supplemental intake of Ca or CaD ≥4 days/week can decrease the risk of depressive symptoms in older adults, although CaD supplements may be more effective.

KEYWORDS:

Calcium; depressive symptoms; older adults; vitamin D

PMID:
31886816
DOI:
10.1007/s12603-019-1278-7

Supplemental Content

Loading ...
Support Center