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EMBO J. 2019 Dec 30:e104112. doi: 10.15252/embj.2019104112. [Epub ahead of print]

Towards the unified principles of transcription termination.

Author information

1
Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, USA.
2
Howard Hughes Medical Institute, New York University School of Medicine, New York, NY, USA.

Abstract

Discovery of the role of bacterial RNase J1 in termination of transcription suggests common allosteric principles and mechanistic congruency of termination between bacteria and eukaryotes, in which an unrelated RNase Xrn2/Rat1 plays a similar role.

PMID:
31886560
DOI:
10.15252/embj.2019104112

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